The world this wiki

The idea of LLM Wiki applied to a year of the Economist. Have an LLM keep a wiki up-to-date about companies, people & countries while reading through all articles of the economist from Q2 2025 until Q2 2026.

DOsinga/the_world_this_wiki

people|Circular reasoning

Paul Mischel

American cancer researcher at Stanford University. In 2012 he was the first to discover that cancer cells use extra-chromosomal DNA (ecDNA)—tiny circular bodies of DNA that escape from chromosomes—to develop drug resistance at rates far faster than Mendel's laws of inheritance would normally allow. His work, published in Cell in April 2026, showed that ecDNA is present in about 20% of human cancer samples and overwhelmingly carries defence mechanisms that help tumour cells replicate and evade destruction. He has identified the "anchor proteins" that allow ecDNA to reintegrate into chromosomes as promising therapeutic targets.

There is no cure for birth and death other than to enjoy the interval. -- George Santayana